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David J. Looney

David J. Looney


  • Fellow, American College of Physicians

  • Member, California HIV and AIDS Research Program Advisory Council

Current Position(s): 

  • Staff Physician & HIV Lead Clinician, VASDHS (Medicine, Infectious Disease)

  • Associate Professor of Medicine IR, UCSD

  • Leader, Center for AIDS Research Genomics & Sequencing Core

  • Co-chair, VASDHS Removable Medical Equipment Committee, Co-chair VASDHS Antimicrobial stewardship Committee, Member, VASDHS Infection Prevention and Control Committee

Personal Statement: 

Dr. Looney serves as principal investigator and director of the UCSD CFAR Genomics and Sequencing Core supporting multiple HIV-cure related projects by providing via cutting-edge, quantitative integration assays using next-generation sequencing (NGS) capable of characterizing clonal (non-replicative) expansion of HIV and advanced viral quantitation for cure studies using droplet-digital PCR.  He also has interests in system-biology approaches to diagnostics and gene therapy, including development of single cell yeast diagnostics and accurate identification and precise eradication of cells latently infected with HIV using lentiviral or other custom vector constructs.

Professional History:

  • Staff Physician, VA San Diego Diego Health System, UCSD Hospitals, 2015-Present

  • Infection Control Officer, VASDHS, 2005-2013

  • Associate Professor In Residence, UCSD, 1996-Present

  • Research Scientist, Veterans Medical Research Foundation, 1998-Present

  • Assistant Professor of Medicine In Residence, UCSD, 1989-1996

  • VASDHS Infectious Diseases and Internal Medicine Staff Physician, 1989-Present

  • General Leonard Wood Army Community Hospital, Internal Medicine Staff, 1982-1984

  • Guest researcher, Cellular Immunology, San Antonio State Chest Hospital, 1984-1986

  • Walter Reed Army Medical Center. Infectious Disease Clinic Staff, Staff Researcher, 1986-1989

  • Guest researcher, Laboratory of Tumor Cell Biology, NCI, NIH, Bethesda, MD, 1986-1989

  • Asst. Prof. Medicine, Uniformed Services University of Health Sciences, Bethesda, MD, 1989-1989


  • B.S. Physics Washington University, St. Louis, MO, 1974

  • M.D., U. Missouri School of Medicine, Columbia, MO,1979

  • Internship & Residency in Internal Medicine, Letterman Army Medical Center, San Francisco, CA, 1979-1982

  • Fellowship in Infectious Diseases, Brook Army Medical Center, San Antonio. TX, 1984-1986,

  • Tropical Medicine Course, Walter Reed Army Institute of Research, Washington, DC,1986

  • Postdoctoral training, NIH/NCI/Laboratory of Tumor Cell Biology, Bethesda, MD, 1986-1989


  • Final Honors for Scholastic Excellence, Washington University, 1974

  • Doctor of Medicine, cum laude, UMC School of Medicine, 1979

  • AMA Physicians Recognition Award, 2002

  • Invited speaker, Keystone Symposium on RNA in Gene Regulation, 2005

  • Invited Speaker: 22nd Annual Stony Brook Symposium on Molecular Biology on Micro, 2005

  • RNAs and gene silencing

  • Recipient of James B. Pendleton Trust award ($191,235) ABI 3500XL DNA analyzer, 2011

  • Recipient of JBPT award ($116,630) Ion Torrent Personal Genome Machine, 2012               

  • Recipient of JBPT award ($29,000) for Covaris DNA fragmenter, 2013

  • Elected to Fellowship in the American College of Physicians, 2014


National/Global Website: National Center for Biotechnology Information

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